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April 15, 2021 by G. Saldana

Texas A&M researchers leaders in study of COVID-19 blocking enzyme

Collaborative study shows K777 effective in combatting SARS-CoV-2 virus 

Photo of Thomas Meek, Ph.D., in his lab
Thomas Meek, Ph.D., professor in the Department of Biochemisty and Biophysics, is one of the key researchers in the collaborative study. (Texas A&M AgriLife photo)

An enzyme inhibitor could become a new weapon in the arsenal to fight COVID-19 as a result of collaborative research by Texas A&M University, the University of Texas Medical Branch – Galveston, the University of California San Diego and others.

The SARS-CoV-2 virus associated with COVID-19 is highly contagious and has led to a global pandemic. To date, more than 130 million people worldwide have been infected and more than 2.8 million have died from COVID-19.   

The study, recently published on the ACS Chemical Biology website, shows that small concentrations of an enzyme inhibitor called K777 strongly impede the infection of several cell lines by SARS-CoV-2, which causes COVID-19. It also demonstrated the efficacy of K777 in reducing the ability of the virus to infect host cell lines without causing harm to the host cells.

Story continues at AgriLife Today

Filed Under: News

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